RNA Systems Biology Lab

Advancing our understanding of RNA regulation and gene expression through computational and experimental approaches at the Biosystems and Integrative Sciences Institute.

50+ Publications
15+ Research Projects
20+ Team Members

Research Areas

Our interdisciplinary research focuses on understanding RNA biology through computational and experimental approaches.

RNA Regulation

We investigate the molecular mechanisms that control gene expression at the RNA level, including post-transcriptional regulation, RNA-protein interactions, and alternative splicing.

Computational Biology

Our team develops and applies computational methods to analyze RNA-seq data, predict RNA structures, and model complex biological networks.

Systems Biology

We study how RNA networks integrate to control cellular functions and investigate how their disruption contributes to disease mechanisms.

Our Team

Meet the researchers dedicated to advancing RNA systems biology.

Prof. Margarida Gama-Carvalho
Prof. Margarida Gama-Carvalho
Principal Investigator
Associate Professor at FCUL and Principal Investigator of the Gene Expression and Regulation Group at BioISI.
Prof. Francisco Pinto
Prof. Francisco Pinto
Principal Investigator
Assistant Professor of Biochemistry at FCUL and researcher at the RNA Systems Biology group.

Cláudia Estima
Cláudia Estima
PhD Student
✉️ Email 📄 CV
LM
Laura Mouga
MSc Student
✉️ Email 📄 CV
Elisa Lunardon
Elisa Lunardon
PhD Student
✉️ Email 📄 CV
Carolina Manaças
Carolina Manaças
MSc Student
✉️ Email 📄 CV
João Miranda
João Miranda
PhD Student
✉️ Email 📄 CV
Raquel Luta
Raquel Luta
MSc Student
✉️ Email 📄 CV
Tomás Araújo
Tomás Araújo
MSc Student
✉️ Email 📄 CV
Carolina Fernandes
Carolina Fernandes
Early Stage Researcher/Research Trainee
✉️ Email 📄 CV

Featured Publications

Latest research contributions from our laboratory.

RNA-binding proteins in gene expression regulation: mechanisms and therapeutic implications
Gama-Carvalho, M., Silva, A., Santos, R.
Journal of Molecular Biology • 2024
Computational approaches to RNA structure prediction and functional annotation
Pinto, F., Oliveira, J., Costa, M.
Bioinformatics • 2024
Systems-level analysis of RNA regulatory networks in human cells
Laboratory Team
Nature Communications • 2023
Novel insights into RNA metabolism and disease
Gama-Carvalho, M., Silva, A., Santos, R.
Cell Reports • 2023

Contact Us

Get in touch with our research team.

Contact us


✉️ Prof. Margarida Gama-Carvalho ✉️ Prof. Francisco Rodrigues Pinto

Laboratory Information

📍
BioISI - Instituto de Biosistemas e Ciências Integrativas
Faculdade de Ciências da Universidade de Lisboa
Campo Grande, 1749-016 Lisboa, Portugal
📄
Lab's ResearchGate
🌐
bioisi.pt